Avoiding premature death in epilepsy.
نویسنده
چکیده
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منابع مشابه
A Brief Overview of Epilepsy with Emphasis on Children
Epilepsy is a brain disorder in which a person has repeated seizures over time. A seizure is a sudden change in the electrical and chemical activity in the brain. A single seizure that does not happen again is NOT epilepsy. Most children with epilepsy live a normal life. Certain types of childhood epilepsy go away or improve with age, usually in the late teens or 20s. Nearly 80% of people with ...
متن کاملSpecific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome.
Heterozygous loss-of-function mutations in the brain sodium channel Na(V)1.1 cause Dravet syndrome (DS), a pharmacoresistant infantile-onset epilepsy syndrome with comorbidities of cognitive impairment and premature death. Previous studies using a mouse model of DS revealed reduced sodium currents and impaired excitability in GABAergic interneurons in the hippocampus, leading to the hypothesis ...
متن کاملPremature mortality in people with epilepsy.
People with epilepsy are at increased risk of premature death, with a mortality rate that is 2–3 times higher than the general population (Cockerell et al, 1994). Premature death in people with epilepsy is associated with disease-linked factors (such as status epilepticus), sudden unexpected death in epilepsy (SUDEP) or underlying disease (for example, brain tumour) (National Sentinel Clinical ...
متن کاملMortality in paediatric epilepsy.
The reasons for premature death in paediatric epilepsy are reviewed with reference to recent studies reported in the literature. Ways of informing families of children with epilepsy about the risk of death are discussed, and recommendations for personal practice given.
متن کاملThe long-term risk of premature mortality in people with epilepsy.
People with epilepsy have an increased risk of premature death. The risk is highest soon after onset of seizures. We report the findings of a long-term follow-up population-based study of people with epilepsy with regards to premature mortality. The National General Practice Study of Epilepsy is a prospective study flagged at the National Health Service Information Centre in the UK. Over 1000 p...
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ورودعنوان ژورنال:
- BMJ
دوره 350 شماره
صفحات -
تاریخ انتشار 2015